Amlodipine benazepril and hydrochlorothiazide

Are you looking for an effective solution to control hypertension?

Introducing Amlodipine benazepril and hydrochlorothiazide – a powerful combination that helps you manage high blood pressure and reduce the risk of heart attack and stroke.

With Amlodipine benazepril and hydrochlorothiazide, you get the benefits of two proven medications in one convenient pill.

Amlodipine benazepril relaxes and widens your blood vessels, making it easier for your heart to pump blood through your body.

Hydrochlorothiazide helps your body get rid of excess salt and water, reducing the fluid buildup that can increase blood pressure.

Take control of your hypertension today with Amlodipine benazepril and hydrochlorothiazide – the smart choice for managing high blood pressure.

Table of Contents

Indications and usage

Amlodipine benazepril and hydrochlorothiazide is a combination medication that is used to treat high blood pressure (hypertension) in adults. This medication contains three different substances: amlodipine, benazepril, and hydrochlorothiazide.

Amlodipine

Amlodipine is a calcium channel blocker that relaxes and widens the blood vessels, making it easier for the heart to pump blood. It helps lower blood pressure and reduces the strain on the heart.

Benazepril

Benazepril is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking the action of a certain enzyme that causes blood vessels to narrow. By inhibiting this enzyme, benazepril helps blood vessels relax and widen, resulting in lower blood pressure.

Hydrochlorothiazide

Hydrochlorothiazide is a diuretic medication that helps the body get rid of excess salt and water. By reducing fluid volume, hydrochlorothiazide helps to lower blood pressure.

This combination medication is usually prescribed when treatment with either amlodipine, benazepril, or hydrochlorothiazide alone is not sufficient to control blood pressure. It may also be used for other purposes as determined by your healthcare provider.

It is important to follow your healthcare provider’s instructions and take this medication as directed. Do not adjust your dosage or stop taking the medication without consulting your healthcare provider.

Contraindications and warnings

Before starting treatment with Amlodipine benazepril and hydrochlorothiazide, it is important to consider the contraindications and warnings associated with this medication. Acontraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it may cause to the patient. It is essential to be knowledgeable about these contraindications in order to ensure the safety and efficacy of the medication.

Contraindications

Amlodipine benazepril and hydrochlorothiazide should not be used in the following situations:

Patients with known hypersensitivity to any of the ingredients in the medication
Patients with a history of angioedema related to previous treatment with an ACE inhibitor
Pregnant women, as there is a potential risk of fetal harm
Breastfeeding women, as it is unknown whether the medication passes into breast milk and may harm the infant
Patients with severe renal impairment (creatinine clearance less than 30 mL/min) who are not receiving dialysis
Patients with anuria (inability to produce urine)

Warnings

There are several important warnings that should be considered when using Amlodipine benazepril and hydrochlorothiazide:

Hypotension: This medication may cause excessive lowering of blood pressure, especially in patients with volume or salt depletion, heart failure, or those who are severely renally impaired. Blood pressure should be closely monitored during treatment.
Renal Impairment: The use of Amlodipine benazepril and hydrochlorothiazide is not recommended in patients with severe renal impairment. In patients with lesser degrees of impairment, periodic monitoring of renal function is advised.
Electrolyte and Metabolic Imbalances: This medication may cause electrolyte imbalances such as hypokalemia, hyponatremia, and hypochloremic alkalosis. Serum electrolyte levels should be monitored periodically.
Acute Myopia and Angle-Closure Glaucoma: Amlodipine benazepril and hydrochlorothiazide should be discontinued if patients develop acute visual changes or eye pain. These symptoms may indicate a serious ocular condition.

It is crucial to follow the recommended dosage and administration guidelines, as well as adhere to the contraindications and warnings, to ensure the safe and effective use of Amlodipine benazepril and hydrochlorothiazide. Always consult with a healthcare professional or pharmacist for further information and guidance.

Contraindications and warnings

Before taking amlodipine benazepril and hydrochlorothiazide, it is important to be aware of the contraindications and warnings associated with this medication.

Contraindications

Do not take this medication if you are allergic to amlodipine, benazepril, hydrochlorothiazide, or any other ingredients in the medication.
It is contraindicated in patients with a history of angioedema or hereditary angioedema.
Avoid using amlodipine benazepril and hydrochlorothiazide if you have severe renal impairment (creatinine clearance less than 30 mL/min).
Do not take this medication if you are currently taking aliskiren in patients with diabetes.

Warnings

There are several important warnings that you should be aware of before taking amlodipine benazepril and hydrochlorothiazide:

This medication should not be used during pregnancy as it may harm the unborn baby. Use effective contraception while taking this medication.
It is important to avoid excessive sweating or dehydration, as this can lead to a drop in blood pressure and electrolyte imbalance.
If you have a history of liver disease or kidney disease, consult your doctor before taking this medication.
Amlodipine benazepril and hydrochlorothiazide may interact with other medications, so inform your doctor or pharmacist about all the drugs you are currently taking.
This medication may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.
It is important to monitor your blood pressure and kidney function regularly while taking this medication.
If you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek medical attention immediately.

By being aware of the contraindications and warnings, you can ensure the safe and effective use of amlodipine benazepril and hydrochlorothiazide.

Side effects

When taking Amlodipine benazepril and hydrochlorothiazide, it is important to be aware of potential side effects. While not all individuals will experience them, it is still important to understand the possible risks.

Common side effects of Amlodipine benazepril and hydrochlorothiazide may include dizziness, headache, fatigue, or stomach upset. These side effects are typically mild and go away on their own as the body adjusts to the medication.

However, it is important to seek medical attention if any of the following side effects occur:

Chest pain or palpitations: This may indicate a serious heart condition and should be evaluated by a healthcare professional.
Severe dizziness or fainting: This could be a sign of low blood pressure and should be addressed promptly.
Signs of an allergic reaction: This may include rash, itching, swelling, severe dizziness, or difficulty breathing. If any of these symptoms occur, immediate medical attention is necessary.
Unusual bleeding or bruising: This may be a sign of a more serious condition and should be evaluated by a healthcare professional.
Signs of kidney problems: This may include a decrease in urine output, swelling in the ankles or feet, or changes in urine color. If any of these symptoms occur, it is important to consult a healthcare professional.

Drug interactions

When taking Amlodipine benazepril and hydrochlorothiazide, it is important to be aware of potential drug interactions. Certain medications may interact with this combination and can cause harmful effects or reduce the effectiveness of the drugs.

It is important to inform your healthcare provider about all prescription and over-the-counter medications, as well as any herbal supplements or vitamins you are taking, before starting Amlodipine benazepril and hydrochlorothiazide. Be sure to mention the following medications:

Medication	Type	Potential Interaction
Lithium	Mood stabilizer	Amlodipine benazepril and hydrochlorothiazide may increase the levels of lithium in the blood, leading to lithium toxicity.
Potassium-sparing diuretics	Diuretic	Taking Amlodipine benazepril and hydrochlorothiazide together with potassium-sparing diuretics can increase the risk of hyperkalemia, a condition characterized by high levels of potassium in the blood.
Nonsteroidal anti-inflammatory drugs (NSAIDs)	Pain reliever	NSAIDs may reduce the effectiveness of Amlodipine benazepril and hydrochlorothiazide in lowering blood pressure.
Statins	Cholesterol-lowering drug	Amlodipine benazepril and hydrochlorothiazide may increase the risk of muscle pain and weakness when taken together with statins.

These are just a few examples of potential drug interactions. Always consult your healthcare provider for a complete list of medications that may interact with Amlodipine benazepril and hydrochlorothiazide.

It is important to remember that drug interactions can occur even with medications that are not listed here. It is always best to talk to your healthcare provider or pharmacist before starting any new medications.